Cadherin 12 抗体 (Middle Region)
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北京 101111
Quick Overview for Cadherin 12 抗体 (Middle Region) (ABIN2782614)
抗原
See all Cadherin 12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- CDH12 Antibody - middle region
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序列
- DTQEGVIKLK KPLDFETKKA YTFKVEASNL HLDHRFHSAG PFKDTATVKI
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against CDH12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDH12
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anti-Cadherin 12 (AA 56-605) antibody
适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 12 antibody适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 12 (AA 324-373) antibody适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 12 antibody (Biotin)适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Cadherin 12 antibody (HRP)适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Cadherin 12 antibody适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 12 (Internal Region) antibody适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 12 (AA 1-794) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin 12 (AA 372-470) antibody适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1B4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46400-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Cadherin 12
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别名
- CDH12
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背景
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Background Information: CDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Gene Name: Cadherin 12, type 2 (N-cadherin 2)
Alternative Symbols: CDHB
Protein Name: Cadherin-12
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分子量
- 82kDa
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基因ID
- 1010
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NCBI登录号
- NP_004052
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UniProt
- P55289
抗原
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