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Cadherin 12 抗体 (Middle Region)

This anti-Cadherin 12 antibody is a 兔 多克隆 antibody detecting Cadherin 12 in WB. Suitable for 人, 大鼠, 小鼠, 犬, 豚鼠, 兔, Cow, 马 和 斑马鱼.
产品编号 ABIN2782614
发货至: 中国

Quick Overview for Cadherin 12 抗体 (Middle Region) (ABIN2782614)

抗原

See all Cadherin 12 抗体
Cadherin 12

适用

人, 大鼠, 小鼠, 犬, 豚鼠, 兔, Cow, 马, 斑马鱼

宿主

  • 50
  • 2

克隆类型

  • 51
  • 1
多克隆

标记

  • 16
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cadherin 12 antibody is un-conjugated

应用范围

  • 25
  • 25
  • 19
  • 13
  • 13
  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    DTQEGVIKLK KPLDFETKKA YTFKVEASNL HLDHRFHSAG PFKDTATVKI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against CDH12. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CDH12
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 794 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Cadherin 12

    别名

    CDH12

    背景

    CDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
    Alias Symbols: CDHB, FLJ34857
    Protein Interaction Partner: CDH7, CDH18,
    Protein Size: 794

    分子量

    82 kDa

    基因ID

    1010

    NCBI登录号

    NM_004061, NP_004052

    UniProt

    P55289
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