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Oncostatin M Receptor 抗体 (Middle Region)

OSMR 适用: 人, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782613
发货至: 中国
  • 抗原 See all Oncostatin M Receptor (OSMR) 抗体
    Oncostatin M Receptor (OSMR)
    抗原表位
    • 15
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Middle Region
    适用
    • 51
    • 16
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 犬, 豚鼠, 马, 兔
    宿主
    • 46
    • 6
    • 1
    • 1
    克隆类型
    • 49
    • 5
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Oncostatin M Receptor antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LLEKKTGYSQ ELAPSDNPHV LVDTLTSHSF TLSWKDYSTE SQPGFIQGYH
    预测反应
    Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 92%
    产品特性
    This is a rabbit polyclonal antibody against OSMR. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human OSMR
    Top Product
    Discover our top product OSMR Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 979 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Oncostatin M Receptor (OSMR)
    别名
    OSMR (OSMR 产品)
    别名
    OSMRB antibody, PLCA1 antibody, oncostatin M receptor antibody, OSMR antibody, Osmr antibody
    背景
    Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
    Protein Interaction Partner: UBC, CUL5, GAPDH, IL6ST, OSM, JAK2, JAK1, ERBB2,
    Protein Size: 979
    分子量
    110 kDa
    基因ID
    9180
    NCBI登录号
    NM_003999, NP_003990
    UniProt
    Q99650
    途径
    JAK/STAT Signaling, Growth Factor Binding
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