Oncostatin M Receptor 抗体 (Middle Region)
Quick Overview for Oncostatin M Receptor 抗体 (Middle Region) (ABIN2782613)
抗原
See all Oncostatin M Receptor (OSMR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LLEKKTGYSQ ELAPSDNPHV LVDTLTSHSF TLSWKDYSTE SQPGFIQGYH
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预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 92%
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产品特性
- This is a rabbit polyclonal antibody against OSMR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human OSMR
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anti-Oncostatin M Receptor (OSMR) (AA 503-749) antibody
OSMR 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 1-342) antibodyOSMR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 1-342) antibodyOSMR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 513-760) antibodyOSMR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 410-652) antibodyOSMR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 120-193) antibodyOSMR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (Internal Region) antibodyVerified OSMR 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Oncostatin M Receptor (OSMR) (AA 141-240) antibodyOSMR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-Oncostatin M Receptor (OSMR) antibodyOSMR 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 979 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Oncostatin M Receptor (OSMR)
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别名
- OSMR
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背景
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Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC150626, MGC150627, MGC75127, OSMRB, PLCA1
Protein Interaction Partner: UBC, CUL5, GAPDH, IL6ST, OSM, JAK2, JAK1, ERBB2,
Protein Size: 979 -
分子量
- 110 kDa
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基因ID
- 9180
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NCBI登录号
- NM_003999, NP_003990
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UniProt
- Q99650
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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