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ADAM15 抗体 (Middle Region)

This anti-ADAM15 antibody is a 兔 多克隆 antibody detecting ADAM15 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig 和 兔.
产品编号 ABIN2782601
发货至: 中国

Quick Overview for ADAM15 抗体 (Middle Region) (ABIN2782601)

抗原

See all ADAM15 抗体
ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

适用

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  • 13
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  • 1
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  • 1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔

宿主

  • 33
  • 5
  • 2
  • 1

克隆类型

  • 32
  • 7
多克隆

标记

  • 26
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
This ADAM15 antibody is un-conjugated

应用范围

  • 30
  • 17
  • 15
  • 7
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  • 5
  • 3
  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    QPAAPLCLQT ANTRGNAFGS CGRNPSGSYV SCTPRDAICG QLQCQTGRTQ

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 79%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ADAM15. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ADAM15
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 862 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

    别名

    ADAM15

    背景

    ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: MDC15
    Protein Interaction Partner: BANP, NUP62, RBPMS, UBC, SP4, FHL3, FBXO6, SH3PXD2A, SRC, PTK6, MAPK3, MAPK1, NCK1, GRB2, SNX30, SH3RF3, SNX9, SH3GLB1, PACSIN3, ARHGEF6, ARHGEF7, SORBS2, YES1, NPHP1, LYN, LCK, HCK, FYN, SH3D19, SH3RF1, SORBS3, SNX33, SORBS1, TRIP13, SH3GL2, ABL1, MAD2L1
    Protein Size: 862

    分子量

    70 kDa

    基因ID

    8751

    NCBI登录号

    NM_207196, NP_997079

    UniProt

    Q71S69
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