Dystrobrevin beta 抗体 (C-Term)
Quick Overview for Dystrobrevin beta 抗体 (C-Term) (ABIN2782578)
抗原
See all Dystrobrevin beta (DTNB) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- ASQPTPEKAQ QNPTLLAELR LLRQRKDELE QRMSALQESR RELMVQLEEL
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against DTNB. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DTNB
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 567 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))
-
别名
- DTNB
-
背景
-
DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC17163, MGC57126
Protein Interaction Partner: CEP55, ABI3, GGA1, NUP62, MTUS2, HMG20A, ABI2, PPFIA1, VCP, TRAF2, KRT31, DTNB, DMD, ZBTB9, TXLNA, KRT40, SPZ1, DTNBP1, USHBP1, NDEL1, CEP63, MLC1, UBC, PRTFDC1, SNTG2, SNTG1, CCDC85B, TSACC, KIF5A, BEGAIN, PPFIBP2, UTRN, SNTA1, KIF5B,
Protein Size: 567 -
分子量
- 64 kDa
-
基因ID
- 1838
-
NCBI登录号
- NM_033148, NP_149160
-
UniProt
- O60941
抗原
-