NMT1 抗体 (N-Term)
Quick Overview for NMT1 抗体 (N-Term) (ABIN2782574)
抗原
See all NMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TMEEASKRSY QFWDTQPVPK LGEVVNTHGP VEPDKDNIRQ EPYTLPQGFT
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against NMT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 496 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).
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: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).
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- NMT1 (N-Myristoyltransferase 1 (NMT1))
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别名
- NMT1
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背景
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Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1).
Alias Symbols: NMT
Protein Interaction Partner: C14orf166, RTCB, DIMT1, NELFB, EDC4, IGF2BP3, PDCD6, POLR1C, EIF2B2, EIF2B3, YBX3, RPL38, RPL23A, RPL19, RFC4, QARS, PA2G4, YBX1, HNRNPM, MRE11A, MAP2, ILF2, IARS, HNRNPU, FLII, FKBP3, DYNC1LI2, DHX9, DDX1, ABCF1, nef, UBC, CSNK2A1, gag, ARL5A, CABP2, MAR
Protein Size: 496 -
分子量
- 57 kDa
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基因ID
- 4836
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NCBI登录号
- NM_021079, NP_066565
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UniProt
- P30419
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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