PFAS 抗体 (N-Term)
(2 references)Quick Overview for PFAS 抗体 (N-Term) (ABIN2782529)
抗原
See all PFAS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ESIMSTQESS NPNNVLKFCD NSSAIQGKEV RFLRPEDPTR PSRFQQQQGL
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预测反应
- Cow: 83%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 79%
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产品特性
- This is a rabbit polyclonal antibody against PFAS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PFAS
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anti-Phosphoribosylformylglycinamidine Synthase (PFAS) (AA 184-213), (N-Term) antibody
PFAS 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25413 unconjugated
anti-Phosphoribosylformylglycinamidine Synthase (PFAS) (AA 1064-1302) antibodyPFAS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoribosylformylglycinamidine Synthase (PFAS) (AA 252-301) antibodyPFAS 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoribosylformylglycinamidine Synthase (PFAS) (AA 1-300) antibodyPFAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1338 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 7, pp. 2528-33, (2013) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 7, pp. 2528-33, (2013) (PubMed).
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- PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))
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别名
- PFAS
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背景
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Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis. Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.
Alias Symbols: FGAMS, FGARAT, KIAA0361, PURL
Protein Interaction Partner: UBC, SUMO2, TNRC6B, GINS3, ISOC1, BZW2, DCPS, MAT2B, ABHD14A, ERP44, PDCD10, FERMT2, NPEPPS, CNBP, YWHAZ, VCL, RAP1GDS1, PAK2, MSN, LDHB, HSPA9, EIF5, EEF2, ECHS1, DFFA, CKB, CAPN1, SGTA, XIAP, UBR1, USP28, PPP6R3, ZNF593, SEPHS1, CHERP, PRDX6, USP14, UBD
Protein Size: 1338 -
分子量
- 145 kDa
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基因ID
- 5198
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NCBI登录号
- NM_012393, NP_036525
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UniProt
- O15067
抗原
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