SMC4 抗体 (N-Term)
Quick Overview for SMC4 抗体 (N-Term) (ABIN2782504)
抗原
See all SMC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SGRTESPATA AETASEELDN RSLEEILNSI PPPPPPAMTN EAGAPRLMIT
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against SMC4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMC4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1288 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))
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别名
- SMC4
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背景
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SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: UBC, SUMO2, LGR4, RPA3, RPA2, RPA1, RNF2, NCAPH, SMC2, SSSCA1, NCAPD2, TBC1D4, PLEC, AP3S1, CDK9, NCAPG, CCAR2, RABL6, TOPBP1, FBXO6, UBD, HDAC11, MYC, Nfe2l2, NEDD8, CDK2, SIRT7, NCAPH2, NCAPD3, RAD21, TRAF3IP1, SUMO1, HDAC1, tat, DNMT3B,
Protein Size: 1288 -
分子量
- 147 kDa
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基因ID
- 10051
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NCBI登录号
- NM_001002800, NP_001002800
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UniProt
- Q9NTJ3
抗原
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