Heat Shock 70kDa Protein 4 (HSPA4) (Middle Region) 抗体

ABIN2782468 产品详细信息, 供应商: Log in to see
抗原
  • hs24/p52
  • hspa4-a
  • osp94
  • pg-2
  • APG-2
  • HS24/P52
  • HSPH2
  • RY
  • hsp70
  • hsp70RY
  • 70kDa
  • AI317151
  • Hsp110
  • Hsp70RY
  • mKIAA4025
  • Hsp70
  • irp94
  • hspa4
  • wu:fi30e11
  • zgc:55743
  • zgc:77413
  • heat shock protein family A (Hsp70) member 4
  • heat shock protein family A (Hsp70) member 4 S homeolog
  • heat shock protein 4
  • heat shock protein family A member 4
  • heat shock protein 4b
  • HSPA4
  • hspa4.S
  • Hspa4
  • hspa4b
抗原表位
Middle Region
7
5
4
3
2
2
2
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
111
83
78
67
49
48
48
48
22
20
20
18
18
16
16
8
3
3
2
2
2
1
1
1
宿主

64
46
3
克隆类型
多克隆
标记
非结合性
5
5
4
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
110
52
49
47
14
8
8
2
1
1
1
选项
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human HSPA4
Blocking Peptide Blocking peptide for this product available: ABIN978305
序列 PIKIRFQESE ERPKLFEELG KQIQQYMKII SSFKNKEDQY DHLDAADMTK
预测反应 Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
产品特性 This is a rabbit polyclonal antibody against HSPA4. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 HSPA4 (HSPA4 Antibody 摘要)
背景 HSPA4(Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.
Alias Symbols: APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2
Protein Interaction Partner: TP53, CDC25C, CDK1, AGTRAP, ERLIN2, HUWE1, Slc12a3, APPBP2, PSMD10, UBC, SUMO2, SUMO3, SIK2, MAP3K11, VHL, UIMC1, PRKCG, PRKCD, STUB1, HIF1A, ENDOG, HSPA8, TRIM5, USP19, PA2G4, WWOX, NDRG1, GZMA, GART, CRMP1, CDKN2A, CARS, PPM1G, PPAT, KARS, FAM114A1, HSP
Protein Size: 840
分子量 94 kDa
基因ID 3308
NCBI登录号 NM_002154, NP_002145
UniProt P34932
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 840 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Heat Shock 70kDa Protein 4 (HSPA4) (Middle Region) antibody (ABIN2782468) Host: Rabbit Target Name: HSPA4 Sample Type: Human 721_B Antibody Dilution: 1.0ug/ml ...
Western Blotting (WB) image for anti-Heat Shock 70kDa Protein 4 (HSPA4) (Middle Region) antibody (ABIN2782468) WB Suggested Anti-HSPA4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positiv...
背景 Kim, Jiang, Du, Wang: "PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1." in: Molecular cell, Vol. 30, Issue 2, pp. 239-47, 2008 (PubMed).

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