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CTH 抗体 (C-Term)

This anti-CTH antibody is a 兔 多克隆 antibody detecting CTH in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782464
发货至: 中国

Quick Overview for CTH 抗体 (C-Term) (ABIN2782464)

抗原

See all CTH 抗体
CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

适用

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人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This CTH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CTH. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CTH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 405 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." in: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

  • 抗原

    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

    别名

    CTH

    背景

    CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
    Alias Symbols: MGC9471
    Protein Interaction Partner: GUCD1, WDYHV1, RECK, CTH, PTMA, GMDS, CAPN2, ATIC, SDCBP2, UBC, ELAVL1,
    Protein Size: 405

    分子量

    44 kDa

    基因ID

    1491

    NCBI登录号

    NM_001902, NP_001893

    UniProt

    P32929

    途径

    ER-Nucleus Signaling, Warburg Effect
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