PAICS 抗体 (N-Term)
Quick Overview for PAICS 抗体 (N-Term) (ABIN2782454)
抗原
See all PAICS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ATAEVLNIGK KLYEGKTKEV YELLDSPGKV LLQSKDQITA GNAARKNHLE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against PAICS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAICS
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 425 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
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别名
- PAICS
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背景
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PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, PAIS
Protein Interaction Partner: L3MBTL2, PAICS, HUWE1, UBC, FUS, WWOX, QRICH1, SWAP70, FARSB, SUPT5H, SET, PRKCSH, FXR2, NUDT18, SMARCD1, PRKAG1, FN1, NIF3L1, TP53BP1, UNK, GINS4, TMEM177, RPAP1, SSSCA1, TACC3, STUB1, PUM1, ZPR1, UBE2B, TTC1, NDUFV1, GART, UBD, CUL3, CDK2, TERF1, SIRT7,
Protein Size: 425 -
分子量
- 47 kDa
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基因ID
- 10606
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NCBI登录号
- NM_001079524, NP_001072992
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UniProt
- P22234
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途径
- Chromatin Binding
抗原
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