SKAP1 抗体 (N-Term)
Quick Overview for SKAP1 抗体 (N-Term) (ABIN2782452)
抗原
See all SKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RDHILRGFQQ IKARYYWDFQ PQGGDIGQDS SDDNHSGTLG LSLTSDAPFL
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预测反应
- Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against SKAP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SKAP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 359 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
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别名
- SKAP1
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背景
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SKAP1 Is a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
Alias Symbols: SCAP1, SKAP55
Protein Interaction Partner: FAM102A, PRAM1, SH2D4A, BLCAP, APP, LCK, FYN, FYB, SRC, LYN, PTPRC, GRB2, SKAP1,
Protein Size: 359 -
分子量
- 41 kDa
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基因ID
- 8631
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NCBI登录号
- NM_003726, NP_003717
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UniProt
- Q86WV1
抗原
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