CENPA 抗体 (N-Term)
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北京 101111
Quick Overview for CENPA 抗体 (N-Term) (ABIN2782448)
抗原
See all CENPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CENPA Antibody - N-terminal region
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序列
- MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE
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预测反应
- Human: 100%, Mouse: 90%, Rat: 90%
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产品特性
- This is a rabbit polyclonal antibody against CENPA. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CENPA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46040-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CENPA (Centromere Protein A (CENPA))
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别名
- CENPA
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背景
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Background Information: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Gene Name: Centromere protein A
Alternative Symbols: CenH3, CENP-A
Protein Name: Histone H3-like centromeric protein A
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分子量
- 16kDa
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基因ID
- 1058
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NCBI登录号
- NP_001800
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UniProt
- P49450
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途径
- Chromatin Binding, Maintenance of Protein Location
抗原
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