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CENPA 抗体 (N-Term)

This anti-CENPA antibody is a 兔 多克隆 antibody detecting CENPA in WB 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN2782448
发货至: 中国
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Quick Overview for CENPA 抗体 (N-Term) (ABIN2782448)

抗原

See all CENPA 抗体
CENPA (Centromere Protein A (CENPA))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CENPA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE

    预测反应

    Human: 100%, Mouse: 90%, Rat: 90%

    产品特性

    This is a rabbit polyclonal antibody against CENPA. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CENPA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 140 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CENPA (Centromere Protein A (CENPA))

    别名

    CENPA

    背景

    Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
    Alias Symbols: CenH3, CENP-A
    Protein Interaction Partner: HIST1H4A, HIST1H2AB, H3F3A, HIST1H2BB, DIAPH3, DIAPH1, NPM1, HIST1H1A, H2AFZ, H2AFX, CENPC, CENPB, HIST3H2BB, HIST4H4, CENPT, CENPU, CENPM, CENPH, CENPN, HJURP, SUPT16H, H2AFY, AURKB, HIST1H3E, HIST2H2AC, SSRP1, RUVBL1, XRCC5, PRKDC, HNRNPU, EIF4A1, DDX5,
    Protein Size: 140

    分子量

    16 kDa

    基因ID

    1058

    NCBI登录号

    NM_001809, NP_001800

    UniProt

    P49450

    途径

    Chromatin Binding, Maintenance of Protein Location
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