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MTHFD2 抗体 (N-Term)

MTHFD2 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782446
发货至: 中国
  • 抗原 See all MTHFD2 抗体
    MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 19
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 马, Cow, 斑马鱼, Saccharomyces cerevisiae
    宿主
    • 15
    • 4
    克隆类型
    • 17
    • 2
    多克隆
    标记
    • 19
    This MTHFD2 antibody is un-conjugated
    应用范围
    • 17
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB)
    序列
    LPLPEHIDER RICNAVSPDK DVDGFHVINV GRMCLDQYSM LPATPWGVWE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against MTHFD2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MTHFD2
    Top Product
    Discover our top product MTHFD2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 350 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原
    MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
    别名
    MTHFD2 (MTHFD2 产品)
    别名
    nmdmc antibody, AW558851 antibody, NMDMC antibody, wu:fb38b11 antibody, wu:fe12e11 antibody, zgc:91891 antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase L homeolog antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like S homeolog antibody, methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase antibody, mthfd2.L antibody, MTHFD2 antibody, mthfd2 antibody, mthfd2l.S antibody, Mthfd2 antibody
    背景
    MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in multiple transcripts encoding different isoforms. This gene has a pseudogene on chromosome 7.
    Alias Symbols: NMDMC
    Protein Interaction Partner: NAGK, HUWE1, UBC, MDM2, nef, DHX40, GCC1, DHX29, CUL3, ELAVL1, MINOS1, PARP3, PSMD13,
    Protein Size: 350
    分子量
    35 kDa
    基因ID
    10797
    NCBI登录号
    NM_006636, NP_006627
    UniProt
    P13995
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