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RRM2 抗体 (N-Term)

RRM2 适用: 人, 大鼠, 豚鼠, 马, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782440
发货至: 中国
  • 抗原 See all RRM2 抗体
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    抗原表位
    • 15
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 豚鼠, 马, Cow, 犬
    宿主
    • 49
    • 5
    克隆类型
    • 41
    • 13
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2 antibody is un-conjugated
    应用范围
    • 37
    • 14
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PALSGTRVLA SKTARRIFQE PTEPKTKAAA PGVEDEPLLR ENPRRFVIFP
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against RRM2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human RRM2
    Top Product
    Discover our top product RRM2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 389 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lane, Yu, Lackey, Chen, Marzluff, Cook: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).

  • 抗原
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    别名
    RRM2 (RRM2 产品)
    别名
    R2 antibody, RR2 antibody, RR2M antibody, AA407299 antibody, rrm2 antibody, rr2m antibody, cb111 antibody, chunp6884 antibody, r2 antibody, ribonucleotide reductase regulatory subunit M2 antibody, ribonucleotide reductase M2 antibody, ribonucleotide reductase M2, gene 2 L homeolog antibody, ribonucleotide reductase M2, gene 1 antibody, ribonucleotide reductase M2 polypeptide antibody, RRM2 antibody, Rrm2 antibody, rrm2.2.L antibody, rrm2.1 antibody, rrm2 antibody
    背景
    RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: R2, RR2M, RR2
    Protein Interaction Partner: DNM1L, UBC, gag-pol, RBMX, PCMT1, NONO, UBD, SKP2, NR1H4, RRM1, CCNF, ELAVL1, KAT5, RRM2B, CDH1, TP53, CDK1,
    Protein Size: 389
    分子量
    45 kDa
    基因ID
    6241
    NCBI登录号
    NM_001034, NP_001025
    UniProt
    P31350
    途径
    Mitotic G1-G1/S Phases
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