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RRM2 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-RRM2 antibody (ABIN2782440) specifically detects RRM2 in WB. The antibody is reactive with 人, 大鼠, 豚鼠, 马, Cow 和 犬 samples.
产品编号 ABIN2782440
发货至: 中国
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Quick Overview for RRM2 抗体 (N-Term) (ABIN2782440)

抗原

See all RRM2 抗体
RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

人, 大鼠, 豚鼠, 马, Cow, 犬

宿主

  • 72
  • 10
兔

克隆类型

  • 51
  • 30
  • 1
多克隆

标记

  • 28
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This RRM2 antibody is un-conjugated

应用范围

  • 51
  • 20
  • 17
  • 13
  • 13
  • 13
  • 12
  • 11
  • 10
  • 8
  • 3
  • 2
Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    原理

    RRM2 Antibody - N-terminal region

    序列

    PALSGTRVLA SKTARRIFQE PTEPKTKAAA PGVEDEPLLR ENPRRFVIFP

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against RRM2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RRM2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46031-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Lane, Yu, Lackey, Chen, Marzluff, Cook: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).

  • 抗原

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    别名

    RRM2

    背景

    Targeted Subunit: M2

    Background Information: RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Ribonucleotide reductase M2

    Alternative Symbols: R2, RR2, RR2M, C2orf48

    Protein Name: Ribonucleoside-diphosphate reductase subunit M2

    分子量

    45kDa

    基因ID

    6241

    NCBI登录号

    NP_001025

    UniProt

    P31350

    途径

    Mitotic G1-G1/S Phases
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