PRIM1 抗体 (N-Term)
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- 抗原 See all PRIM1 抗体
- PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 马, 豚鼠, 斑马鱼, 犬, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SQYYRWLNYG GVIKNYFQHR EFSFTLKDDI YIRYQSFNNQ SDLEKEMQKM
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against PRIM1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRIM1
- Top Product
- Discover our top product PRIM1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 420 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))
- 别名
- PRIM1 (PRIM1 产品)
- 别名
- AI324982 antibody, p49 antibody, dnapol-alpha50 antibody, DNA primase, p49 subunit antibody, DNA primase subunit 1 antibody, DNA primase subunit 1 S homeolog antibody, Prim1 antibody, PRIM1 antibody, prim1.S antibody
- 背景
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The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. PRIM1 is the small, 49 kDa primase subunit.The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
Alias Symbols: MGC12308, p49
Protein Interaction Partner: FAM96B, CIAO1, UBC, MMS19, MDC1, POLA2, PRIM2, POLE, POLA1, COPS6, RPA3, RPA2, RPA1, RAE1, MRPL38, TP53, XRCC5,
Protein Size: 420 - 分子量
- 50 kDa
- 基因ID
- 5557
- NCBI登录号
- NM_000946, NP_000937
- UniProt
- P49642
- 途径
- Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interactome
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