GUCY1B3 抗体 (N-Term)
Quick Overview for GUCY1B3 抗体 (N-Term) (ABIN2782430)
抗原
See all GUCY1B3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LIEEKESKEE DFYEDLDRFE ENGTQESRIS PYTFCKAFPF HIIFDRDLVV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against GUCY1B3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GUCY1B3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 619 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
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别名
- GUCY1B3
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背景
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Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM].
Alias Symbols: GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1
Protein Interaction Partner: APP, STUB1, UBC, AGAP1, GUCY1A2, HSP90AA1, NOS3,
Protein Size: 619 -
分子量
- 70 kDa
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基因ID
- 2983
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NCBI登录号
- NM_000857, NP_000848
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UniProt
- Q02153
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途径
- Transition Metal Ion Homeostasis
抗原
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