GM2A 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for GM2A 抗体 (N-Term) (ABIN2782426)
抗原
See all GM2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- GM2A Antibody - N-terminal region
-
序列
- SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
-
预测反应
- Guinea Pig: 83%, Human: 100%
-
产品特性
- This is a rabbit polyclonal antibody against GM2A. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46007-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- GM2A (GM2 Ganglioside Activator (GM2A))
-
别名
- GM2A
-
背景
-
Background Information: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Gene Name: GM2 ganglioside activator
Alternative Symbols: SAP-3, GM2-AP
Protein Name: Ganglioside GM2 activator
-
分子量
- 21
-
基因ID
- 2760
-
NCBI登录号
- NP_000396
-
UniProt
- P17900
抗原
-