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PFKL 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-PFKL antibody specifically detects PFKL in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 和 斑马鱼 samples.
产品编号 ABIN2782359
发货至: 中国
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Quick Overview for PFKL 抗体 (Middle Region) (ABIN2782359)

抗原

See all PFKL 抗体
PFKL (Phosphofructokinase, Liver (PFKL))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼

宿主

  • 42
  • 5

克隆类型

  • 43
  • 4
多克隆

标记

  • 31
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PFKL antibody is un-conjugated

应用范围

  • 35
  • 19
  • 18
  • 6
  • 6
  • 5
  • 5
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    RTNVLGHLQQ GGAPTPFDRN YGTKLGVKAM LWLSEKLREV YRKGRVFANA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against PFKL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human PFKL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 568 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • 抗原

    PFKL (Phosphofructokinase, Liver (PFKL))

    别名

    PFKL

    背景

    Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. PFK from muscle is a homotetramer of M subunit, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. PFKL represents the L subunit.
    Alias Symbols: DKFZp686G1648, DKFZp686L2097, FLJ30173, FLJ40909, PFK-B
    Protein Interaction Partner: KRTAP10-7, GTPBP3, PFKL, KRTAP5-9, FUS, STAU1, UBC, EGFR, RNF2, rev, ZC3HC1, PSMD9, FBXO6, YWHAQ, HDAC6, PRPF40A, TESK1, PFKM, MYD88, ITGA4, FN1, PCBP3, PRDX3, PFKP, APP, ATN1, RAD21, SNW1, TERF2, ATG101, TAF13, TAF10, DMWD, COPS6, KRTAP4-12,
    Protein Size: 568

    分子量

    64 kDa

    基因ID

    5211

    NCBI登录号

    NM_002626

    UniProt

    P17858

    途径

    Negative Regulation of Hormone Secretion, Warburg Effect
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