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CSTB 抗体 (Middle Region)

CSTB 适用: 人, 大鼠, 小鼠, Pig, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782349
发货至: 中国
  • 抗原 See all CSTB 抗体
    CSTB (Cystatin B (Stefin B) (CSTB))
    抗原表位
    • 22
    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 85
    • 20
    • 19
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠, Pig, 马, 兔, 犬
    宿主
    • 85
    • 17
    • 1
    • 1
    克隆类型
    • 85
    • 18
    多克隆
    标记
    • 46
    • 15
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSTB antibody is un-conjugated
    应用范围
    • 65
    • 36
    • 34
    • 16
    • 14
    • 13
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    AGTNYFIKVH VGDEDFVHLR VFQSLPHENK PLTLSNYQTN KAKHDELTYF
    预测反应
    Dog: 92%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 79%, Rabbit: 77%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against CSTB. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CSTB
    Top Product
    Discover our top product CSTB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 98 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CSTB (Cystatin B (Stefin B) (CSTB))
    别名
    CSTB (CSTB 产品)
    别名
    CST6 antibody, EPM1 antibody, EPM1A antibody, PME antibody, STFB antibody, ULD antibody, CSTB antibody, Cyb antibody, Epm1 antibody, Stfb antibody, MGC189005 antibody, pme antibody, cst6 antibody, epm1 antibody, stfb antibody, AA960480 antibody, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 antibody, ATCYS6 antibody, ATCYSB antibody, cystatin B antibody, LOC100008600 antibody, LOC100136235 antibody, CPI1 antibody, cystatin B antibody, cystatin B (stefin B) antibody, cystatin 14a, tandem duplicate 2 antibody, cystatin-B antibody, CSTB antibody, Cstb antibody, cstb antibody, cst14a.2 antibody, CYSB antibody, cpi1 antibody, LOC101123265 antibody
    背景
    CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
    Alias Symbols: CST6, EPM1, PME, STFB, ULD, EPM1A
    Protein Interaction Partner: UBC, SARNP, DPP7, BAG3, CFTR, ECT2, SEC24A, NUDC, MAT2A, FLNB, DCUN1D1, CUL3, RAD21, SPRY2, CTSL, CTSD, CTSH, CTSB, CST3, VHL,
    Protein Size: 98
    分子量
    11 kDa
    基因ID
    1476
    NCBI登录号
    NM_000100, NP_000091
    UniProt
    P04080
    途径
    Response to Water Deprivation
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