CSTB 抗体 (Middle Region)
Quick Overview for CSTB 抗体 (Middle Region) (ABIN2782349)
抗原
See all CSTB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- AGTNYFIKVH VGDEDFVHLR VFQSLPHENK PLTLSNYQTN KAKHDELTYF
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预测反应
- Dog: 92%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 79%, Rabbit: 77%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against CSTB. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CSTB
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anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal M2-F1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyCSTB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal M1-C1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyVerified CSTB 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Cystatin B (Stefin B) (CSTB) antibodyCSTB 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 51-98) antibodyCSTB 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C6 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 98 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CSTB (Cystatin B (Stefin B) (CSTB))
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别名
- CSTB
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背景
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CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Alias Symbols: CST6, EPM1, PME, STFB, ULD, EPM1A
Protein Interaction Partner: UBC, SARNP, DPP7, BAG3, CFTR, ECT2, SEC24A, NUDC, MAT2A, FLNB, DCUN1D1, CUL3, RAD21, SPRY2, CTSL, CTSD, CTSH, CTSB, CST3, VHL,
Protein Size: 98 -
分子量
- 11 kDa
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基因ID
- 1476
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NCBI登录号
- NM_000100, NP_000091
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UniProt
- P04080
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途径
- Response to Water Deprivation
抗原
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