Liver Arginase 抗体 (N-Term)
Quick Overview for Liver Arginase 抗体 (N-Term) (ABIN2782309)
抗原
See all Liver Arginase (ARG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SAKSRTIGII GAPFSKGQPR GGVEEGPTVL RKAGLLEKLK EQECDVKDYG
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交叉反应
- 牛, 人, 小鼠, 猪, 兔, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%
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产品特性
- This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1
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应用备注
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WB Suggested Anti-ARG1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 322 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, (2008) (PubMed).
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: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, (2008) (PubMed).
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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别名
- Arginase-1
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背景
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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
Protein Size: 322 -
分子量
- 35 kDa
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基因ID
- 383
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NCBI登录号
- NM_000045, NP_000036
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UniProt
- P05089
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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