DEGS1 抗体 (N-Term)
Quick Overview for DEGS1 抗体 (N-Term) (ABIN2782243)
抗原
See all DEGS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV
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预测反应
- Cow: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against DEGS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DEGS1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 323 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))
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别名
- DEGS1
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背景
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DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Alias Symbols: DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
Protein Interaction Partner: UBC, NAGPA, UBD, EGFR, TSSC1, SURF4, SLC16A1, PYGM,
Protein Size: 323 -
分子量
- 38 kDa
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基因ID
- 8560
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NCBI登录号
- NM_003676, NP_003667
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UniProt
- O15121
抗原
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