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ZP2 抗体 (C-Term)

ZP2 适用: 人, 大鼠, 马, 兔, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782230
发货至: 中国
  • 抗原 See all ZP2 抗体
    ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 马, 兔, 豚鼠, Cow, 犬
    宿主
    • 19
    • 4
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZP2 antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PDSFPQWNVV VDGCAYDLDN YQTTFHPVGS SVTHPDHYQR FDMKAFAFVS
    预测反应
    Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against ZP2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ZP2
    Top Product
    Discover our top product ZP2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 745 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))
    别名
    ZP2 (ZP2 产品)
    别名
    fa12e07 antibody, wu:fa12e07 antibody, zgc:152728 antibody, zp2 antibody, Zp-2 antibody, ZPA antibody, zona pellucida glycoprotein 2, tandem duplicate 5 antibody, zona pellucida glycoprotein 2 antibody, zp2.5 antibody, Zp2 antibody, ZP2 antibody
    背景
    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. ZP2 is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
    Alias Symbols: ZPA, Zp-2
    Protein Interaction Partner: ZPBP, ACR,
    Protein Size: 745
    分子量
    68 kDa
    基因ID
    7783
    NCBI登录号
    NM_003460, NP_003451
    UniProt
    Q05996
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