TGFB2 抗体 (Middle Region)
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- 抗原 See all TGFB2 抗体
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 绵羊, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGFB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NLVKAEFRVF RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against TGFB2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TGFB2
- Top Product
- Discover our top product TGFB2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 414 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- 别名
- TGFB2 (TGFB2 产品)
- 别名
- LDS4 antibody, TGF-beta2 antibody, tgf-beta2 antibody, tgfb2-A antibody, BB105277 antibody, Tgf-beta2 antibody, Tgfb-2 antibody, TGF-beta 2 antibody, Tgfbr2T antibody, TGFB2 antibody, TGFbeta2 antibody, MGF antibody, TGF-B2 antibody, transforming growth factor beta 2 antibody, transforming growth factor beta 2 L homeolog antibody, transforming growth factor, beta 2 antibody, transforming growth factor, beta receptor 2 antibody, TGFB2 antibody, tgfb2.L antibody, Tgfb2 antibody, Tgfbr2 antibody, tgfb2 antibody
- 背景
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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC116892, TGF-beta2
Protein Interaction Partner: CEBPA, UBC, VASN, PZP, LTBP3, TGFBR3, FMOD, VTN, TGFB3, TGFB2, TGFBR2, TGFBR1, TGFB1, ENG, CTGF, BMP2, APP, TGFBRAP1, DAXX, DCN,
Protein Size: 414 - 分子量
- 46 kDa
- 基因ID
- 7042
- NCBI登录号
- NM_003238, NP_003229
- UniProt
- P61812
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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