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TGFB2 抗体 (Middle Region)

This anti-TGFB2 antibody (ABIN2782223) is a Rabbit Polyclonal antibody detecting TGFB2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse, Sheep, Guinea Pig, Zebrafish (Danio rerio).
产品编号 ABIN2782223
发货至: 中国

Quick Overview for TGFB2 抗体 (Middle Region) (ABIN2782223)

抗原

See all TGFB2 抗体
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

适用

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人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 马, 绵羊, 豚鼠, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This TGFB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    NLVKAEFRVF RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against TGFB2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TGFB2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 414 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    别名

    TGFB2

    背景

    This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: MGC116892, TGF-beta2
    Protein Interaction Partner: CEBPA, UBC, VASN, PZP, LTBP3, TGFBR3, FMOD, VTN, TGFB3, TGFB2, TGFBR2, TGFBR1, TGFB1, ENG, CTGF, BMP2, APP, TGFBRAP1, DAXX, DCN,
    Protein Size: 414

    分子量

    46 kDa

    基因ID

    7042

    NCBI登录号

    NM_003238, NP_003229

    UniProt

    P61812

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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