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TAPBP 抗体 (C-Term)

This anti-TAPBP antibody is a 兔 多克隆 antibody detecting TAPBP in WB 和 IHC. Suitable for 人, 绵羊, Cow 和 Pig.
产品编号 ABIN2782218
发货至: 中国

Quick Overview for TAPBP 抗体 (C-Term) (ABIN2782218)

抗原

See all TAPBP 抗体
TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

适用

  • 23
  • 9
  • 6
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人, 绵羊, Cow, Pig

宿主

  • 23

克隆类型

  • 23
多克隆

标记

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  • 1
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This TAPBP antibody is un-conjugated

应用范围

  • 23
  • 9
  • 8
  • 3
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term

    序列

    GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS

    预测反应

    Cow: 86%, Human: 100%, Pig: 86%, Sheep: 86%

    产品特性

    This is a rabbit polyclonal antibody against TAPBP. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human TAPBP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 448 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

    别名

    TAPBP

    背景

    TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
    Alias Symbols: NGS17, TAPA, TPN, TPSN
    Protein Interaction Partner: UBC, PDIA3, Tap2, ELAVL1, US3, TAP1, B2M, COPG1, COPG2, COPB1, HLA-C, HLA-A, CALR,
    Protein Size: 448

    分子量

    46 kDa

    基因ID

    6892

    NCBI登录号

    NM_003190, NP_003181

    UniProt

    O15533
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