PIGA 抗体 (Middle Region)
(1 reference)Quick Overview for PIGA 抗体 (Middle Region) (ABIN2782189)
抗原
See all PIGA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- SVKSLCEGLE KAIFQLKSGT LPAPENIHNI VKTFYTWRNV AERTEKVYDR
-
预测反应
- Cow: 86%, Dog: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against PIGA. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PIGA
-
-
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (AA 443-484) antibody
PIGA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (AA 179-228) antibodyPIGA 适用: 人, 小鼠, Cow, Pig, 兔, 犬, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (AA 117-166) antibodyPIGA 适用: 人, Cow, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) antibodyPIGA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (AA 455-484), (C-Term) antibodyPIGA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31291 unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (Middle Region) antibodyPIGA 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA) (AA 147-177), (C-Term) antibodyPIGA 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 169 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 12, pp. 3081-4, (2007) (PubMed).
-
: "On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 12, pp. 3081-4, (2007) (PubMed).
-
- PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
-
别名
- PIGA
-
背景
-
PIGA is a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene.This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.
Alias Symbols: GPI3, PIG-A
Protein Interaction Partner: UBC, ELAVL1, PIGY, DPM2, PIGQ, PIGH, PIGP,
Protein Size: 169 -
分子量
- 19 kDa
-
基因ID
- 5277
-
NCBI登录号
- NM_020473, NP_065206
-
UniProt
- B3KUV7
-
途径
- Inositol Metabolic Process
抗原
-
