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PI3 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects PI3 in WB. It exhibits reactivity toward 人.
产品编号 ABIN2782186
发货至: 中国
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Quick Overview for PI3 抗体 (N-Term) (ABIN2782186)

抗原

See all PI3 抗体
PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PI3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    RASSFLIVVV FLIAGTLVLE AAVTGVPVKG QDTVKGRVPF NGQDPVKGQV

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against PI3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PI3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 117 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

    别名

    PI3

    背景

    PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
    Protein Interaction Partner: EVPL, CELA1, LOR, KRT1, CSTA,
    Protein Size: 117

    分子量

    6 kDa

    基因ID

    5266

    NCBI登录号

    NM_002638, NP_002629

    UniProt

    P19957
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