Fc epsilon RI/FCER1A 抗体 (Middle Region)
Quick Overview for Fc epsilon RI/FCER1A 抗体 (Middle Region) (ABIN2782151)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IYYKDGEALK YWYENHNISI TNATVEDSGT YYCTGKVWQL DYESEPLNIT
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预测反应
- Human: 100%, Rabbit: 85%, Rat: 77%
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产品特性
- This is a rabbit polyclonal antibody against FCER1A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FCER1A
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anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibody
FCER1A 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C12-3B6 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 42-103) antibodyFCER1A 适用: 人, 小鼠 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 1F2A9 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) antibodyFCER1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibodyFCER1A 适用: 人 FACS, WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 9E1 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (C-Term) antibodyFCER1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 101-220) antibodyFCER1A 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) antibodyFCER1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibody (APC)FCER1A 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal MAR-1 APC
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 257 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- FCER1A
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背景
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The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139), only the alpha subunit is glycosylated.The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139), only the alpha subunit is glycosylated.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FCE1A, FcERI
Protein Interaction Partner: PDHB, SYK, FCER1A, FCER1G, MS4A2, ITIH2, VAV1,
Protein Size: 257 -
分子量
- 27 kDa
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基因ID
- 2205
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NCBI登录号
- NM_002001, NP_001992
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UniProt
- P12319
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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