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Desmocollin 3 抗体 (N-Term)

This anti-Desmocollin 3 antibody is a 兔 多克隆 antibody detecting Desmocollin 3 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 兔.
产品编号 ABIN2782146
发货至: 中国

Quick Overview for Desmocollin 3 抗体 (N-Term) (ABIN2782146)

抗原

See all Desmocollin 3 (DSC3) 抗体
Desmocollin 3 (DSC3)

适用

人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔

宿主

  • 46
  • 4
  • 1
  • 1

克隆类型

  • 46
  • 6
多克隆

标记

  • 19
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Desmocollin 3 antibody is un-conjugated

应用范围

  • 41
  • 14
  • 13
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    N-Term

    序列

    MQENSLGPFP LFLQQVESDA AQNYTVFYSI SGRGVDKEPL NLFYIERDTG

    预测反应

    Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against DSC3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DSC3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 896 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Desmocollin 3 (DSC3)

    别名

    DSC3

    背景

    DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
    Alias Symbols: CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP
    Protein Interaction Partner: EZH2, env, UBC, UCHL5, RYK, PKP3, PKP4, JUP, CTNNB1,
    Protein Size: 896

    分子量

    85 kDa

    基因ID

    1825

    NCBI登录号

    NM_001941, NP_001932

    UniProt

    Q14574
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