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P-Cadherin 抗体 (N-Term)

This anti-P-Cadherin antibody is a 兔 多克隆 antibody detecting P-Cadherin in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 兔.
产品编号 ABIN2782138
发货至: 中国

Quick Overview for P-Cadherin 抗体 (N-Term) (ABIN2782138)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔

宿主

  • 96
  • 20
  • 2
  • 2

克隆类型

  • 96
  • 22
  • 1
多克隆

标记

  • 54
  • 12
  • 11
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This P-Cadherin antibody is un-conjugated

应用范围

  • 100
  • 53
  • 41
  • 36
  • 26
  • 20
  • 15
  • 15
  • 13
  • 13
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    AVSENGASVE DPMNISIIVT DQNDHKPKFT QDTFRGSVLE GVLPGTSVMQ

    预测反应

    Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against CDH3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CDH3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 829 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    P-Cadherin (CDH3)

    别名

    CDH3

    背景

    CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
    Alias Symbols: CDHP, HJMD, PCAD
    Protein Interaction Partner: UBC, CTNND1, CTNNB1, CTNNA1, CDH3, JUP, CDH1,
    Protein Size: 829

    分子量

    91 kDa

    基因ID

    1001

    NCBI登录号

    NM_001793, NP_001784

    UniProt

    P22223
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