IL-10RA 抗体 (N-Term)
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- 抗原 See all IL-10RA (IL10RA) 抗体
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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抗原表位
- N-Term
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适用
- 人, 大鼠, Cow, 马, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-10RA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
- 预测反应
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Rat: 77%
- 产品特性
- This is a rabbit polyclonal antibody against IL10RA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL10RA
- Top Product
- Discover our top product IL10RA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 578 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- 别名
- IL10RA (IL10RA 产品)
- 别名
- IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
- 背景
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IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Alias Symbols: CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Interaction Partner: BTRC, UBC, IL10RB, JAK1, IL10,
Protein Size: 578 - 分子量
- 61 kDa
- 基因ID
- 3587
- NCBI登录号
- NM_001558, NP_001549
- UniProt
- Q13651
- 途径
- Growth Factor Binding
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