IL-10RA 抗体 (N-Term)
Quick Overview for IL-10RA 抗体 (N-Term) (ABIN2782131)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
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预测反应
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Rat: 77%
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产品特性
- This is a rabbit polyclonal antibody against IL10RA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL10RA
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anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 132-235) antibody
IL10RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (Ser560) antibodyIL10RA 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (C-Term) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (pTyr496) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 128-177) antibodyIL10RA 适用: 人, Cow, Pig, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) antibodyIL10RA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 147-175) antibodyIL10RA 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB23343 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 81-180) antibodyIL10RA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 132-235) antibodyIL10RA 适用: 人 WB 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) antibodyIL10RA 适用: 小鼠 FACS, IF, Neut 宿主: 大鼠 Monoclonal 1B1-3a unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 578 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- IL10RA
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背景
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IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Alias Symbols: CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Interaction Partner: BTRC, UBC, IL10RB, JAK1, IL10,
Protein Size: 578 -
分子量
- 61 kDa
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基因ID
- 3587
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NCBI登录号
- NM_001558, NP_001549
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UniProt
- Q13651
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途径
- Growth Factor Binding
抗原
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