COX10 抗体 (Middle Region)
Quick Overview for COX10 抗体 (Middle Region) (ABIN2782122)
抗原
See all COX10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- APGPFDWPCF LLTSVGTGLA SCAANSINQF FEVPFDSNMN RTKNRPLVRG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against COX10. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COX10
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anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 383-410), (C-Term) antibody
COX10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24307 unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 386-414), (C-Term) antibodyCOX10 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) antibodyCOX10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 215-264) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 180-229) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-160) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 443 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
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别名
- COX10
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背景
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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX10 is heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Size: 443 -
分子量
- 49 kDa
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基因ID
- 1352
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NCBI登录号
- NM_001303, NP_001294
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UniProt
- Q12887
抗原
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