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POMT1 抗体 (Middle Region)

POMT1 适用: 人, 小鼠, Cow, Pig, 大鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782091
发货至: 中国
  • 抗原 See all POMT1 抗体
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    抗原表位
    • 15
    • 10
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, Cow, Pig, 大鼠, 犬, 马, 兔
    宿主
    • 43
    克隆类型
    • 43
    多克隆
    标记
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POMT1 antibody is un-conjugated
    应用范围
    • 28
    • 19
    • 17
    • 16
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    LTFQILLLPV VLQHISDHLC RSQLQRSIFS ALVVAWYSSA CHVSNTLRPL
    预测反应
    Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 77%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against POMT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human POMT1
    Top Product
    Discover our top product POMT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 725 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    别名
    POMT1 (POMT1 产品)
    别名
    LGMD2K antibody, MDDGA1 antibody, MDDGB1 antibody, MDDGC1 antibody, RT antibody, AI505244 antibody, protein O-mannosyltransferase 1 antibody, protein-O-mannosyltransferase 1 antibody, POMT1 antibody, Pomt1 antibody
    背景
    POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K).O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB154785.1 1-42 43-2420 AK074874.1 1-2378 2421-2617 BF984005.1 438-634 2618-3080 AL358781.19 127610-128072
    Alias Symbols: FLJ37239, LGMD2K, RT, MDDGA1, MDDGB1, MDDGC1
    Protein Interaction Partner: UBC, POMT2,
    Protein Size: 725
    分子量
    82 kDa
    基因ID
    10585
    NCBI登录号
    NM_001077365, NP_001070833
    UniProt
    B3KQG0
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