CPT1A 抗体 (Middle Region)
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北京 101111
Quick Overview for CPT1A 抗体 (Middle Region) (ABIN2782010)
抗原
See all CPT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LSTSQTPQQQ VELFDLENNP EYVSSGGGFG PVADDGYGVS YILVGENLIN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CPT1A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CPT1A
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anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 191-353) antibody
CPT1A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 301-600) antibodyCPT1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Internal Region) antibodyVerified CPT1A 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 1-100) antibodyCPT1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 461-550) antibodyCPT1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 572-773) antibodyCPT1A 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 606-636) antibodyCPT1A 适用: 人, Cow WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 568-773) antibodyCPT1A 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 684-733) antibodyCPT1A 适用: 人, 小鼠, Cow, Pig, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 1-773) antibodyCPT1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 756 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity." in: European journal of medicinal chemistry, Vol. 127, pp. 379-397, (2017) (PubMed).
: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).
: "New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor ?/? dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression." in: Journal of medicinal chemistry, Vol. 56, Issue 1, pp. 60-72, (2013) (PubMed).
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: "New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity." in: European journal of medicinal chemistry, Vol. 127, pp. 379-397, (2017) (PubMed).
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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别名
- CPT1A
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背景
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The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CPT1, CPT1-L, L-CPT1
Protein Interaction Partner: UBC, SUMO2, LGR4, RNF2, FBXO6, PARK2, LYN, CLN3, HDAC11, KBTBD7, NPDC1, HSPA5, NR4A1, CYBA, CLIC1, SNRNP200, ERLIN1, TOMM40, EIF3C, PCBP1, NDUFV1, NDUFS1, NDUFA2, LPP, CPS1, ATP6V1C1, RHOA, PCK1, BCL2,
Protein Size: 756 -
分子量
- 86 kDa
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基因ID
- 1374
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NCBI登录号
- NM_001031847, NP_001027017
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UniProt
- P50416
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途径
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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