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CPT1A 抗体 (Middle Region)

Name: CPT1A 抗体 (Middle Region)
SKU: ABIN2782010
Availability: OutOfStock

This anti-CPT1A antibody is a 兔多克隆 antibody detecting CPT1A in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊和斑马鱼. This Primary Antibody has been cited in 3+ publications.

WB Suggested Anti-CPT1A Antibody Titration: 0. (CPT1A 抗体 (Middle Region))

Host: Rabbit Target Name: CPT1A Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 1ug/ml (CPT1A 抗体 (Middle Region))

Host: Rabbit Target Name: CPT1A Sample Tissue: Human MDA-MB-435s Whole Cell Antibody Dilution: 1ug/ml (CPT1A 抗体 (Middle Region))

Host: Rabbit Target Name: CPT1A Sample Tissue: Human Stomach Tumor Antibody Dilution: 1ug/ml (CPT1A 抗体 (Middle Region))

Host: Rabbit Target Name: CPT1A Sample Type: 293T Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0. (CPT1A 抗体 (Middle Region))

Sample Type : Human Capan1 cells (Pancreatic cancer cell line) Primary Antibody Dilution : 1:300 Secondary Antibody : Anti-rabbit-AlexaFluor-488 Secondary Antibody Dilution : 1:200 Color/Signal Descriptions : CPT1A: Green DAPI: Blue Gene Name : CPT1A Submitted by : Dr. (CPT1A 抗体 (Middle Region))

IHC

7 images

(3 references)

产品编号 ABIN2782010

发货至: 中国

Quick Overview for CPT1A 抗体 (Middle Region) (ABIN2782010)

抗原

See all CPT1A 抗体

CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This CPT1A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product CPT1A Primary Antibody

抗原表位
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Middle Region

序列

LSTSQTPQQQ VELFDLENNP EYVSSGGGFG PVADDGYGVS YILVGENLIN

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against CPT1A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human CPT1A
anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 497-756) antibody
CPT1A 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 191-353) antibody
CPT1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 301-600) antibody
CPT1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Internal Region) antibody
Verified CPT1A 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 1-100) antibody
CPT1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 461-550) antibody
CPT1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 497-756) antibody
CPT1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 572-773) antibody
CPT1A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 606-636) antibody
CPT1A 适用: 人, Cow WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (AA 568-773) antibody
CPT1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 756 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Piemontese, Cerchia, Laghezza, Ziccardi, Sblano, Tortorella, Iacobazzi, Infantino, Convertini, Dal Piaz, Lupo, Colantuoni, Lavecchia, Loiodice: "New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity." in: European journal of medicinal chemistry, Vol. 127, pp. 379-397, (2017) (PubMed).

Convertini, Menga, Andria, Scala, Santarsiero, Castiglione Morelli, Iacobazzi, Infantino: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).

Laghezza, Pochetti, Lavecchia, Fracchiolla, Faliti, Piemontese, Di Giovanni, Iacobazzi, Infantino, Montanari, Capelli, Tortorella, Loiodice: "New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor ?/? dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression." in: Journal of medicinal chemistry, Vol. 56, Issue 1, pp. 60-72, (2013) (PubMed).
抗原

CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

别名

CPT1A

背景

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CPT1, CPT1-L, L-CPT1
Protein Interaction Partner: UBC, SUMO2, LGR4, RNF2, FBXO6, PARK2, LYN, CLN3, HDAC11, KBTBD7, NPDC1, HSPA5, NR4A1, CYBA, CLIC1, SNRNP200, ERLIN1, TOMM40, EIF3C, PCBP1, NDUFV1, NDUFS1, NDUFA2, LPP, CPS1, ATP6V1C1, RHOA, PCK1, BCL2,
Protein Size: 756

分子量

86 kDa

基因ID

1374

NCBI登录号

NM_001031847, NP_001027017

UniProt

P50416

途径

AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process