ITM2C 抗体 (Middle Region)
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北京 101111
Quick Overview for ITM2C 抗体 (Middle Region) (ABIN2781948)
抗原
See all ITM2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- ITM2C Antibody - middle region
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序列
- EDSLSSQVRT QMELEEDVKI YLDENYERIN VPVPQFGGGD PADIIHDFQR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against ITM2C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Integral Membrane Protein 2C (ITM2C) antibody
ITM2C 适用: 人, 小鼠, 大鼠 ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 27-55), (N-Term) antibodyITM2C 适用: 人 WB 宿主: 兔 Polyclonal RB36714 unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibodyITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44631-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ITM2C (Integral Membrane Protein 2C (ITM2C))
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别名
- ITM2C
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背景
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Background Information: ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.
Gene Name: Integral membrane protein 2C
Alternative Symbols: E25, BRI3, E25C, ITM3, BRICD2C
Protein Name: Integral membrane protein 2C
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分子量
- 30kDa
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基因ID
- 81618
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NCBI登录号
- NP_112188
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UniProt
- Q9NQX7
抗原
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