ITM2C 抗体 (Middle Region)
ITM2C
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, 兔, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
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- 抗原 See all ITM2C 抗体
- ITM2C (Integral Membrane Protein 2C (ITM2C))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITM2C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EDSLSSQVRT QMELEEDVKI YLDENYERIN VPVPQFGGGD PADIIHDFQR
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
- 产品特性
- This is a rabbit polyclonal antibody against ITM2C. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product ITM2C Primary Antibody
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anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 267 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ITM2C (Integral Membrane Protein 2C (ITM2C))
- 别名
- ITM2C (ITM2C 产品)
- 别名
- 3110038L02Rik antibody, BRI3 antibody, Bricd2c antibody, E25 antibody, E25C antibody, ITM3 antibody, BRICD2C antibody, fj35c02 antibody, itm2c antibody, wu:fj35c02 antibody, zgc:66349 antibody, wu:fj52a04 antibody, zgc:92783 antibody, integral membrane protein 2C antibody, integral membrane protein 2Cb antibody, integral membrane protein 2Ca antibody, Itm2c antibody, ITM2C antibody, itm2cb antibody, itm2ca antibody
- 背景
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ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.
Alias Symbols: BRI3, BRICD2C, E25, E25C, ITM3
Protein Interaction Partner: UBC, Dlg4, RYK, BACE1, RNF7, STT3A, MTNR1B, FURIN,
Protein Size: 267 - 分子量
- 30 kDa
- 基因ID
- 81618
- NCBI登录号
- NM_030926, NP_112188
- UniProt
- Q9NQX7
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