ITM2C 抗体 (Middle Region)
This anti-ITM2C antibody is a 兔 多克隆 antibody detecting ITM2C in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, 兔 和 斑马鱼.
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Quick Overview for ITM2C 抗体 (Middle Region) (ABIN2781948)
抗原
See all ITM2C 抗体
ITM2C
(Integral Membrane Protein 2C (ITM2C))
适用
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, 兔, 斑马鱼
宿主
兔
克隆类型
多克隆
标记
This ITM2C antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- Middle Region
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序列
- EDSLSSQVRT QMELEEDVKI YLDENYERIN VPVPQFGGGD PADIIHDFQR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against ITM2C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 267 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ITM2C (Integral Membrane Protein 2C (ITM2C))
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别名
- ITM2C
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背景
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ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.
Alias Symbols: BRI3, BRICD2C, E25, E25C, ITM3
Protein Interaction Partner: UBC, Dlg4, RYK, BACE1, RNF7, STT3A, MTNR1B, FURIN,
Protein Size: 267 -
分子量
- 30 kDa
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基因ID
- 81618
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NCBI登录号
- NM_030926, NP_112188
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UniProt
- Q9NQX7
抗原
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