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Ectodysplasin A 抗体 (Middle Region)

This anti-Ectodysplasin A antibody is a 兔 多克隆 antibody detecting Ectodysplasin A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2781905
发货至: 中国

Quick Overview for Ectodysplasin A 抗体 (Middle Region) (ABIN2781905)

抗原

See all Ectodysplasin A (EDA) 抗体
Ectodysplasin A (EDA)

适用

  • 71
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人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔

宿主

  • 68
  • 6
  • 1

克隆类型

  • 66
  • 6
  • 2
多克隆

标记

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  • 5
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  • 1
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This Ectodysplasin A antibody is un-conjugated

应用范围

  • 63
  • 35
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  • 12
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  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
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    • 8
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    • 3
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    Middle Region

    序列

    HLQGQGSAIQ VKNDLSGGVL NDWSRITMNP KVFKLHPRSG ELEVLVDGTY

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against EDA. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human EDA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 389 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhao, Watt, Battle, Li, Bondow, Duncan: "Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." in: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).

  • 抗原

    Ectodysplasin A (EDA)

    别名

    EDA

    背景

    EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
    Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
    Protein Interaction Partner: OSTCP1, OSTC, NIPAL3, GIMAP5, SEC22A, LEPROTL1, DOLK, PLN, MAL, EMP3, CYB561, ATP6V0C, EDAR, EDA, EDA2R, FURIN,
    Protein Size: 389

    分子量

    41 kDa

    基因ID

    1896

    NCBI登录号

    NM_001005609, NP_001005609

    UniProt

    B7ZLU4

    途径

    Tube Formation
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