B4GALT2 抗体 (Middle Region)
Quick Overview for B4GALT2 抗体 (Middle Region) (ABIN2781899)
抗原
See all B4GALT2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- Middle Region
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                                            序列
- NRISLTGMKI SRPDIRIGRY RMIKHDRDKH NEPNPQRFTK IQNTKLTMKR
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                                            预测反应
- Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 91%, Zebrafish: 93%
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                                            产品特性
- This is a rabbit polyclonal antibody against B4GALT2. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human B4GALT2
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
- 
                        Antigen size: 372 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))
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                                            别名
- B4GALT2
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                                            背景
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                        This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.
 Alias Symbols: B4Gal-T2, B4Gal-T3, beta4Gal-T2
 Protein Interaction Partner: PFDN6,
 Protein Size: 372
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                                            分子量
- 42 kDa
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                                            基因ID
- 8704
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                                            NCBI登录号
- NM_001005417, NP_001005417
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                                            UniProt
- O60909
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                                            途径
- Glycosaminoglycan Metabolic Process
 抗原
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