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Osteoactivin 抗体 (N-Term)

This anti-Osteoactivin antibody is a 兔 多克隆 antibody detecting Osteoactivin in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬 和 兔.
产品编号 ABIN2781893
发货至: 中国

Quick Overview for Osteoactivin 抗体 (N-Term) (ABIN2781893)

抗原

See all Osteoactivin (GPNMB) 抗体
Osteoactivin (GPNMB)

适用

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人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔

宿主

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克隆类型

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多克隆

标记

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This Osteoactivin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN

    特异性

    100 % homologous to both isoforms of hGPNMB

    预测反应

    Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 560 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Osteoactivin (GPNMB)

    别名

    GPNMB

    背景

    GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: HGFIN, NMB
    Protein Interaction Partner: UBC, SMAD4, ITSN2,
    Protein Size: 560

    分子量

    63 kDa

    基因ID

    10457

    NCBI登录号

    NM_002510, NP_002501

    UniProt

    Q14956
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