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Derlin-3 抗体 (C-Term)

DERL3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781869
发货至: 中国
  • 抗原 See all Derlin-3 (DERL3) 抗体
    Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    C-Term
    适用
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 10
    This Derlin-3 antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    YYFLEDVFPN QPGGKRLLQT PGFLKLLLDA PAEDPNYLPL PEEQPGPHLP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human DERL3
    Top Product
    Discover our top product DERL3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 235 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
    别名
    DERL3 (DERL3 产品)
    别名
    1810006I20Rik antibody, 1810063P04Rik antibody, IZP6 antibody, derlin-3 antibody, zgc:63991 antibody, C22orf14 antibody, LLN2 antibody, derlin 3 antibody, Der1-like domain family, member 3 antibody, DERL3 antibody, Derl3 antibody, derl3 antibody
    背景
    DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
    Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
    Protein Interaction Partner: ERN1, UBE2J1, SERPINA1, MFI2, AMFR,
    Protein Size: 235
    分子量
    27 kDa
    基因ID
    91319
    NCBI登录号
    NM_001002862, NP_001002862
    UniProt
    Q96Q80
    途径
    ER-Nucleus Signaling
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