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Derlin-3 抗体 (C-Term)

This anti-Derlin-3 antibody is a 兔 多克隆 antibody detecting Derlin-3 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼 和 马.
产品编号 ABIN2781869
发货至: 中国

Quick Overview for Derlin-3 抗体 (C-Term) (ABIN2781869)

抗原

See all Derlin-3 (DERL3) 抗体
Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马

宿主

  • 11

克隆类型

  • 11
多克隆

标记

  • 11
This Derlin-3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    YYFLEDVFPN QPGGKRLLQT PGFLKLLLDA PAEDPNYLPL PEEQPGPHLP

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human DERL3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 235 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

    别名

    DERL3

    背景

    DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
    Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
    Protein Interaction Partner: ERN1, UBE2J1, SERPINA1, MFI2, AMFR,
    Protein Size: 235

    分子量

    27 kDa

    基因ID

    91319

    NCBI登录号

    NM_001002862, NP_001002862

    UniProt

    Q96Q80

    途径

    ER-Nucleus Signaling
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