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GGCX 抗体 (Middle Region)

This 兔 多克隆 anti-GGCX antibody specifically detects GGCX in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 绵羊 samples.
产品编号 ABIN2781826
发货至: 中国
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Quick Overview for GGCX 抗体 (Middle Region) (ABIN2781826)

抗原

See all GGCX 抗体
GGCX (gamma-Glutamyl Carboxylase (GGCX))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊

宿主

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克隆类型

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多克隆

标记

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This GGCX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    FLLRKLYVFR RSFLMTCISL RNLILGRPSL EQLAQEVTYA NLRPFEAVGE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against GGCX. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GGCX
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 758 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GGCX (gamma-Glutamyl Carboxylase (GGCX))

    别名

    GGCX

    背景

    GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ26629, VKCFD1
    Protein Interaction Partner: UBC, DCP2, FBXO6, F9, F10, F7, F2, PROC, BGLAP,
    Protein Size: 758

    分子量

    87 kDa

    基因ID

    2677

    NCBI登录号

    NM_000821, NP_000812

    UniProt

    P38435

    途径

    SARS-CoV-2 Protein Interactome
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