Thyroperoxidase 抗体 (N-Term)
Quick Overview for Thyroperoxidase 抗体 (N-Term) (ABIN2781812)
抗原
See all Thyroperoxidase (TPO) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GASNTALARW LPPVYEDGFS QPRGWNPGFL YNGFPLPPVR EVTRHVIQVS
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预测反应
- Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Yeast: 83%
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产品特性
- This is a rabbit polyclonal antibody against TPO. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPO
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- Thyroid Peroxidase
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背景
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This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Protein Interaction Partner: DUOX1, TXNDC11,
Protein Size: 611 -
分子量
- 67 kDa
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基因ID
- 7173
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途径
- Thyroid Hormone Synthesis
抗原
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