UGT1A1 抗体 (N-Term)
Quick Overview for UGT1A1 抗体 (N-Term) (ABIN2781804)
抗原
See all UGT1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DGSHWLSMLG AIQQLQQRGH EIVVLAPDAS LYIRDGAFYT LKTYPVPFQR
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预测反应
- Horse: 86%, Human: 100%, Mouse: 79%, Rat: 82%
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产品特性
- This is a rabbit polyclonal antibody against UGT1A1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A1
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anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 1-200) antibody
UGT1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 316-533) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 395-482) antibodyUGT1A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) antibodyUGT1A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 65-90), (N-Term) antibodyUGT1A1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB22607 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 251-300) antibodyUGT1A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 36-85) antibodyUGT1A1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 533 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
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别名
- UGT1A1
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背景
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UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GNT1, HUG-BR1, UDPGT, UGT1, UGT1A, BILIQTL1, UDPGT 1-1
Protein Interaction Partner: COPZ1, SEC23B, UGDH, B3GALT1,
Protein Size: 533 -
分子量
- 57 kDa
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基因ID
- 54658
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NCBI登录号
- NM_000463, NP_000454
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UniProt
- P22309
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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