HFE 抗体 (C-Term)
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- 抗原 See all HFE 抗体
- HFE (Hemochromatosis (HFE))
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抗原表位
- C-Term
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适用
- 人, 大鼠, Cow, 犬, 马, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HFE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- FEPKDVLPNG DGTYQGWITL AVPPGEEQRY TCQVEHPGLD QPLIVIWEPS
- 预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Rat: 100%, Zebrafish: 91%
- 产品特性
- This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HFE
- Top Product
- Discover our top product HFE Primary Antibody
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anti-Hemochromatosis (HFE) (AA 115-205) antibody
HFE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Hemochromatosis (HFE) antibodyHFE 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 262-348) antibodyHFE 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (Internal Region) antibodyHFE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 149-198) antibodyHFE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 80-306) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (C-Term) antibodyHFE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) antibodyHFE 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 246 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HFE (Hemochromatosis (HFE))
- 别名
- HFE (HFE 产品)
- 背景
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HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
Protein Interaction Partner: B2M, SYVN1, UBC, TFR2, TFRC,
Protein Size: 246 - 分子量
- 28 kDa
- 基因ID
- 3077
- NCBI登录号
- NM_139008, NP_620577
- 途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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