HFE 抗体 (C-Term)
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北京 101111
Quick Overview for HFE 抗体 (C-Term) (ABIN2781800)
抗原
See all HFE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FEPKDVLPNG DGTYQGWITL AVPPGEEQRY TCQVEHPGLD QPLIVIWEPS
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Rat: 100%, Zebrafish: 91%
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产品特性
- This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HFE
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anti-Hemochromatosis (HFE) (AA 115-205) antibody
HFE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Hemochromatosis (HFE) antibodyHFE 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 262-348) antibodyHFE 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 80-306) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (Internal Region) antibodyHFE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 149-198) antibodyHFE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (C-Term) antibodyHFE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) antibodyHFE 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 246 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HFE (Hemochromatosis (HFE))
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别名
- HFE
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背景
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HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
Protein Interaction Partner: B2M, SYVN1, UBC, TFR2, TFRC,
Protein Size: 246 -
分子量
- 28 kDa
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基因ID
- 3077
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NCBI登录号
- NM_139008, NP_620577
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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